We report a patient with a Brown-Séquard syndrome due to Semple type antirabies vaccine, with subclinical electrophysiological abnormalities, who recovered with immunosuppressants.
Sathyanarayana Swamy H, Shankar S K, Chandra P S, Aroor S R, Shivaramakrishna A, Kaliaperumal V G (1985) Neurological complications due to beta-propiolactone (BPL) inactivated antirabies vaccination. J Neurol Sci 63: 111–128.
Toro G, Vergara I and Roman G (1977) Neuroparalytic accidents of antirabies vaccination with SMB vaccine. Arch Neurol 34: 694–700.
Label L S, Batts D H (1982) Transverse myelitis caused by duck embryo rabies vaccine. Arch Neurol 39: 426–430.
Helm E B, Dillmann W, Stille W (1978) Experience with new vaccines in rabies vaccination treatment. Munch Med Wschr 120: 293–296.
Boe E, Nyland H (1980) Guillain-Barre syndrome after vaccination with human diploid cell rabies vaccine. Scand J Infect Dis 12: 231–232.
Uchimura I, Shiraki H (1957) A contribution to the classification and the pathogenesis of demyelinating encephalomyelitis. J Neuropath Exp Neurol 16: 139–208.
Appelbaum E, Greenberg M, Nelson J . (1953). Neurological complications following anti-rabies vaccination. JAMA 151: 188–191.
Hemachudha T, Phanuphak P, Johnson R T, Ratanavongsiri J, Siriprasomsup W (1987) Neurologic complications of Semple-type rabies vaccine: clinical and immunologic studies. Neurology (Minneapolis) 37: 550–556.
Warrell M J, Suntharasamai P, Sinhaseni A, Phanfung R, Falquet J C V, Bunnag D et al (1983) An economical regimen of human diploid cell strain anti-rabies vaccine for post-exposure prophylaxis. Lancet II August 6th: 301–303.
Brij K ishor e, Meharotra M P, Hazra D K, Wahal P K, Bansal O P, Patney N L and Agrawal Y B (1978) A study of circulating anti-bodies in cases receiving antirabic inoculation with reference to the neurological complications. J Ass Phys India 28: 479–484.
Briggs G W and Brown M W (1960) Neurological complications of antirabies vaccine—treatment with corticosteroids. J Am Med Assoc 173: 802–804.
Ferraro A and Roizin L (1953) Experimental allergic encephalomyelitis during and following cortisone acetate treatment. J Neuropath Exp Neurol 12: 373–386.
Garrison S C (1952) Encephalomyelitis complicating antirabies vaccination treated with cortisone. Am J Med 12: 135.
About this article
Cite this article
Sathyanarayana Swamy, H., Vasanth, A. & Kumar, S. Brown-Séquard syndrome due to Semple antirabies vaccine: case report. Spinal Cord 30, 181–183 (1992). https://doi.org/10.1038/sc.1992.52
- Brown-Séquard sydrome
- antirabies vaccine