Abstract
Blood flow of normal biceps and flaccid paralysed anterior tibial muscle was measured in eight patients by means of 133Xe and 51CrEDTA clearance. Exercise as well as papaverin could increase the blood flow significantly in both muscles. Whereas the duration of blood flow increase was found to last longer after exercise the effective perfusion was calculated to be twice as high after papaverin as after exercise in paralysed muscles. Together with the elevation of capillary blood flow a 100 per cent. increase of capillary transport can be observed. From this data the conclusion can be drawn that passive exercise and the local application of papaverin increases capillary blood flow and transport capacity possibly resulting in a faster healing of chronic pressure sores.
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Kety, S S (1949). Measurement of regional circulation by the clearance of radioactive sodium. Amer. Heart J. 38, 321.
Lewis, D H (1972). Measurement of capillary flow and capillary transport. In Hemo-dilution. Theoretical Basis and Clinical Application (Ed. Meßmer, K. & Schmid-Schönbein, H.). Basel-München-Paris, London, New-York, Sydney: S. Karger.
Renkin, E M (1959). Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles. Amer. J. Physiol. 197, 1205.
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Seifert, J., Lob, G., Stoephasius, E. et al. Blood flow in muscles of paraplegic patients under various conditions measured by a double isotope technique. Spinal Cord 10, 185–191 (1972). https://doi.org/10.1038/sc.1972.30
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DOI: https://doi.org/10.1038/sc.1972.30