Antimicrobial peptides have the potential to combat the growing threat of antimicrobial resistance; however, their clinical translation remains challenging. Here, we discuss molecular farming as a sustainable approach to antimicrobial peptide production, outlining different platforms to produce antimicrobial peptides using plants and viral vectors.
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Acknowledgements
We would like to thank members of the genome engineering and synthetic biology laboratory at the King Abdullah University of Science and Technology (KAUST) for insightful discussions.
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M.M.M. conceived the concept and outline for the article; S.C. and M.M.M. wrote the article.
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Chaudhary, S., Mahfouz, M.M. Molecular farming of antimicrobial peptides. Nat Rev Bioeng 2, 3–5 (2024). https://doi.org/10.1038/s44222-023-00149-y
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DOI: https://doi.org/10.1038/s44222-023-00149-y