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Micro- and nanorobots for biomedical applications in the brain

Nature Reviews Bioengineering volume 1, pages 308–310 (2023)Cite this article

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Micro- and nanorobots hold great potential to overcome brain barriers for the treatment of brain diseases. They can be delivered to the brain by local injection, intranasal application, or systemic administration. Combining active propulsion with biological and chemical approaches or external physical stimuli can improve brain targeting.

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Fig. 1: Strategies to introduce micro- and nanorobots into the brain for drug and cell delivery.

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Acknowledgements

This work was supported by National Science Foundation grant 1931214. We thank H. Han, J. Seong and J. Joo for the valuable inputs.

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  1. These authors contributed equally: Jounghyun Yoo, Songsong Tang.

Authors and Affiliations

  1. Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, CA, USA

    Jounghyun Yoo, Songsong Tang & Wei Gao

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  1. Jounghyun Yoo
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  2. Songsong Tang
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  3. Wei Gao
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Correspondence to Wei Gao.

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Yoo, J., Tang, S. & Gao, W. Micro- and nanorobots for biomedical applications in the brain. Nat Rev Bioeng 1, 308–310 (2023). https://doi.org/10.1038/s44222-023-00038-4

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