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Neuropsychiatric disorders

A comprehensive matrix of factors contributing to depression

A study drawing on the expansive UK Biobank dataset to explore the lifestyle, genetic and biological underpinnings of mental health highlights the influence of lifestyle on depression risk and suggests that detailed investigations into lifestyle factors, in conjunction with psychological aspects and advanced analysis methods, may reveal a deeper understanding of the complexities of mental health.

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Fig. 1: A modified model of depression including psychological protective factors.

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Correspondence to Oleg N. Medvedev.

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Medvedev, O.N., Krägeloh, C.U. A comprehensive matrix of factors contributing to depression. Nat. Mental Health 1, 702–703 (2023). https://doi.org/10.1038/s44220-023-00126-9

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