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Personality traits linked to risk of brain disorder

The role of personality in brain health remains unclear. A systematic search demonstrated that lower levels of warmth, diligence, sociability and curiosity, and a higher level of nervousness, were predictive of increased risk of brain disorders. Brain structure, inflammation and lipid metabolism partially explain the associations between personality and brain disorders.

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Fig. 1: The associations between personality and brain health.

References

  1. Roberts, B. W. & Yoon, H. J. Personality psychology. Annu. Rev. Psychol. 73, 489–516 (2022). This review article presents the main research directions in the field of personality.

    Article  PubMed  Google Scholar 

  2. Hindley, G. & Alexey, A. S. Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy. Nat. Hum. Behav. https://doi.org/10.1038/s41562-023-01630-9 (2023). This paper reports the linkage of personality with cognition.

    Article  PubMed  Google Scholar 

  3. Sudlow, C. & John, G. UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 12, e1001779 (2015). This paper reports the setting of the UK Biobank.

    Article  PubMed  PubMed Central  Google Scholar 

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This is a summary of: Zhang, Y.-R. et al. Personality traits and brain health: a large prospective cohort study. Nat. Ment. Health https://doi.org/10.1038/s44220-023-00119-8 (2023).

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Personality traits linked to risk of brain disorder. Nat. Mental Health 1, 707–708 (2023). https://doi.org/10.1038/s44220-023-00123-y

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