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Brain imaging

Embracing the heterogeneity in depression neuroimaging

Nature Mental Health volume 1, pages 243–244 (2023)Cite this article

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Unipolar depression is a common mental disorder that is increasingly treated with neuroimaging-guided therapeutics. Cash et al. use brain connectomics in 57 heterogeneous neuroimaging studies to report meta-analytic brain networks linked to aberrant emotional and cognitive processing in individuals with unipolar depression.

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Fig. 1: Heterogeneous neuroimaging findings converge to brain networks related to aberrant emotional and cognitive processing in unipolar depression.

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Authors and Affiliations

  1. Ghent Experimental Psychiatry Lab and 4BRAIN Research Lab, Ghent University Hospital, Department of Head and Skin, Ghent, Belgium

    Debby C. W. Klooster

  2. Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

    Debby C. W. Klooster

  3. Center for Brain Circuit Therapeutics and Department of Psychiatry, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Shan H. Siddiqi

Authors
  1. Debby C. W. Klooster
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  2. Shan H. Siddiqi
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Correspondence to Debby C. W. Klooster.

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Competing interests

D.C.W.K. declares no competing interests. S.H.S. is a scientific consultant for Magnus Medical and a clinical consultant for Acacia Mental Health, Kaizen Brain Center, and Boston Precision Neurotherapeutics. S.H.S. has received investigator-initiated research funding from Neuronetics. S.H.S. has served as a speaker for Brainsway and PsychU.org (unbranded, sponsored by Otsuka). S.H.S. owns intellectual property involving the use of functional connectivity to target TMS.

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Klooster, D.C.W., Siddiqi, S.H. Embracing the heterogeneity in depression neuroimaging. Nat. Mental Health 1, 243–244 (2023). https://doi.org/10.1038/s44220-023-00047-7

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