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Atherosclerosis and inflammation

Identification of inflammatory lipid-associated macrophages in human carotid atherosclerosis

Vascular inflammation is an established risk factor for atherosclerosis progression and associated outcomes. Single-cell RNA sequencing of carotid atherosclerotic plaques identifies a population of lipid-associated macrophages that may contribute to plaque inflammation and clinical events.

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Fig. 1: Schematic depicting a carotid artery atherosclerotic plaque containing two subsets of LAMs.

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Correspondence to Kory Lavine.

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Lavine, K. Identification of inflammatory lipid-associated macrophages in human carotid atherosclerosis. Nat Cardiovasc Res 2, 604–605 (2023). https://doi.org/10.1038/s44161-023-00299-7

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