A strategy for the Ni-catalysed hydrodimerization of two unactivated terminal alkenes to selectively afford linear or methyl-branched alkyl–alkyl products is demonstrated. This method offers a solution to the long-standing challenge of connecting alkenes head-to-head and provides a facile approach to constructing C(sp3)–C(sp3) bonds from readily accessible alkenes.
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This is a summary of: Cheng, L., Liu, J., Chen, Y. & Gong, H. Nickel-catalysed hydrodimerization of unactivated terminal alkenes. Nat. Synth. https://doi.org/10.1038/s44160-023-00239-0 (2023).
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Selective dimerization of terminal alkenes to form alkyl–alkyl products. Nat. Synth 2, 319–320 (2023). https://doi.org/10.1038/s44160-023-00240-7
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DOI: https://doi.org/10.1038/s44160-023-00240-7
