Synthesis of chiral aryl–alkene bond axes is a challenge owing to axial instability and specific substrate requirements. Now, arylboration of alkynes by sequentially using two catalysts yields axially chiral alkenylboronates with excellent stereocontrol.
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Cheng, J.K., Tan, B. Atroposelectivity with two catalysts. Nat. Synth 2, 83–85 (2023). https://doi.org/10.1038/s44160-022-00209-y
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DOI: https://doi.org/10.1038/s44160-022-00209-y
