Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

COMPUTATIONAL NEUROSCIENCE

The role of ADM in brain function

In a recent study a phenomenological model was used to study the effects of activity-dependent myelination (ADM) on network activity and information transmission in the brain. The model explores how the conduction velocity of an axon — and thus the overall transmission delay — varies as a function of neural activity.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Impact of ADM on neural activity.

References

  1. Talidou, A., Frankland, P. W., Mabbott, D. & Lefebvre, J. Nat. Comput. Sci. https://doi.org/10.1038/s43588-022-00315-z (2022).

  2. Hodgkin, A. L. J. Physiol. 94, 560–570 (1939).

    Article  Google Scholar 

  3. Poirazi, P. & Papoutsi, A. Nat. Rev. Neurosci. 21, 303–321 (2020).

    Article  Google Scholar 

  4. Bullock, T. H. J. Physiol. 114, 89–97 (1951).

    Article  Google Scholar 

  5. Arbuthnott, E. R., Boyd, I. A. & Kalu, K. U. J. Physiol. 308, 125–157 (1980).

    Article  Google Scholar 

  6. Chiaravalloti, N. D. & DeLuca, J. Lancet Neurol. 7, 1139–1151 (2008).

    Article  Google Scholar 

  7. Emery, B. Science 330, 779–782 (2010).

    Article  Google Scholar 

  8. Bucher, D. & Goaillard, J. M. Progr. Neurobiol. 94, 307–346 (2011).

    Article  Google Scholar 

  9. Zhang, Y., Bucher, D. & Nadim, F. eLife 6, e25382 (2017).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maurice J. Chacron.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chacron, M.J. The role of ADM in brain function. Nat Comput Sci 2, 628–629 (2022). https://doi.org/10.1038/s43588-022-00320-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s43588-022-00320-2

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing