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Cancer therapy

Targeting network circuitry in glioma

Nature Cancer volume 4, pages 1406–1407 (2023)Cite this article

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The nervous system regulates cancer progression, and the importance of neuron–glioma communication in tumor growth is evident in glioblastoma. This tumor-promoting communication presents a potential therapeutic axis, a concept reinforced by a study that identifies a specific potassium channel complex as a therapeutic target.

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Fig. 1: Targeting signaling between glioma cells and neurons.

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Authors and Affiliations

  1. Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada

    Stephen M. Robbins & Donna L. Senger

  2. Gerald Bronfman Department of Oncology, McGill University, Montreal, Quebec, Canada

    Stephen M. Robbins & Donna L. Senger

Authors
  1. Stephen M. Robbins
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  2. Donna L. Senger
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Corresponding author

Correspondence to Donna L. Senger.

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Competing interests

S.M.R. and D.L.S. are listed on a patent entitled Brain Tumor Targeting Peptides and Methods that has been assigned to Arch Cancer Therapeutics, for which they are founding scientists. This patent is not related to the peptides described here.

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Robbins, S.M., Senger, D.L. Targeting network circuitry in glioma. Nat Cancer 4, 1406–1407 (2023). https://doi.org/10.1038/s43018-023-00640-w

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