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Microbiome

Resisting weight gain with prebiotic fibre

Resistant starch is a prebiotic fibre that is fermented by the gut microbiota and leads to benefits for host physiology. A clinical trial in Nature Metabolism demonstrates weight loss when resistant starch was given to individuals with excess weight.

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Fig. 1: Promoting weight loss with a type 2 resistant-starch prebiotic fibre.

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Acknowledgements

S.P.S was funded by National Institutes of Health grant 5T32DK007056 and 1K08DK134856.

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Correspondence to Sean P. Spencer.

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Carter, M.M., Spencer, S.P. Resisting weight gain with prebiotic fibre. Nat Metab 6, 389–391 (2024). https://doi.org/10.1038/s42255-024-00998-w

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