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METABOLIC HOMEOSTASIS

Prolonged lactation benefits offspring metabolism

Longer duration of breastfeeding is shown to have long-lasting effects in rodents, which lead to an adult phenotype that is resistant to diet-induced obesity and has increased brown adipose tissue activity through a process dependent on hypothalamic FGF21 signalling.

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Fig. 1: Effects of prolonged lactation.

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Correspondence to Kristin I. Stanford.

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Félix-Soriano, E., Stanford, K.I. Prolonged lactation benefits offspring metabolism. Nat Metab 4, 798–799 (2022). https://doi.org/10.1038/s42255-022-00604-x

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