A recent study by Esteghamat et al., published in Nature Genetics, has reported that CELA2A, encoding a pancreatic enzyme, is a novel genetic cause of metabolic syndrome and atherosclerosis.
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Acknowledgements
A.L.G. is a Wellcome Senior Fellow in Basic Biomedical Science (095101/Z/10/Z and 200837/Z/16/Z). A.L.G. is also supported by the Oxford NIHR Biomedical Research Centre. The views expressed in this article are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health.
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Gloyn, A.L. Exocrine or endocrine? A circulating pancreatic elastase that regulates glucose homeostasis. Nat Metab 1, 853–855 (2019). https://doi.org/10.1038/s42255-019-0107-y
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DOI: https://doi.org/10.1038/s42255-019-0107-y