The growth of new blood vessels (angiogenesis) is a bio-energetically demanding process. Surprisingly, the specific role of mitochondria in angiogenesis remains unclear. A study in this issue of Nature Metabolism now demonstrates that mitochondrial respiration is essential for angiogenic growth by controlling endothelial proliferation.
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Andrade, J., Potente, M. Endothelial metabolism—more complex (III) than previously thought. Nat Metab 1, 14–15 (2019). https://doi.org/10.1038/s42255-018-0019-2
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DOI: https://doi.org/10.1038/s42255-018-0019-2
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