While skeletal editing stands as a powerful approach for simplifying synthetic procedures and obtaining complex molecules, viable methodologies remain limited. Now, a smart photoredox protocol, involving the insertion of carbon atoms into the indene core, gives access to a wide library of functionalized naphthalenes.
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Sicignano, M., Costa, P. Drug design via single-carbon atom insertion. Nat Catal 7, 224–226 (2024). https://doi.org/10.1038/s41929-024-01123-6
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DOI: https://doi.org/10.1038/s41929-024-01123-6
