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Statistical design of experiments: the forgotten component of Reduction

Lab Animal volume 53, pages 57–59 (2024)Cite this article

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A strategic and statistically based experimental design is a key component of Reduction, and the backbone of reproducible research. Design basics consist of formal structuring of input variables and clearly defined experimental units. Formal designs can evaluate two or more input factors simultaneously, identify and prioritise the most important inputs, and identify interactions where most discovery occurs.

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Authors and Affiliations

  1. Department of Anesthesiology, University of Florida, Gainesville, FL, USA

    Penny Reynolds

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  1. Penny Reynolds
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Correspondence to Penny Reynolds.

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The author declares no competing interests.

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Reynolds, P. Statistical design of experiments: the forgotten component of Reduction. Lab Anim 53, 57–59 (2024). https://doi.org/10.1038/s41684-024-01334-1

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