Host genetics, housing conditions, and antibiotic treatments impact microbiota diversity and composition, but microbes that inhabit the mouse gut and skin can also influence severity and penetrance of host mutant phenotypes.
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Acknowledgements
MGD is supported by program project grant HG000330 from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH).
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Perry, M.N., Bello, S.M. & Smith, C.L. Know Your Model: Microbiota & phenotypes. Lab Anim 49, 301–302 (2020). https://doi.org/10.1038/s41684-020-00660-4
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DOI: https://doi.org/10.1038/s41684-020-00660-4