Correction to: Scientific Reports https://doi.org/10.1038/s41598-022-17200-4, published online 28 July 2022
The original version of this Article contained an error in Figure 1.
As a result of an error during figure assembly, the C>T cell #1 panel in Figure 1c was a duplication of C>T dog #1 panel in Figure 2d. Figure 1 was replaced to show the correct data. The original Figure 1 is reproduced below for the record.
Correction of a point mutation in donor cells using prime editor (PE). (a) Schematic of PE vector. It consists of a prime editor that can correct SNP at the BICF2S23030416 locus and EGFP as a reporter. (b) Structure and design of PE guide RNA (pegRNA). The bracketed region in orange color indicates the scaffold for pegRNA17. The nucleotide (A) in red indicates the SNP mutation site. (c) Chromatographic analysis of the donor patient cells and C>T cell #1. The red asterisk indicates the target locus and confirms the C to T sequence correction mediated by PE.
The original Article has been corrected.
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Kim, D.E., Lee, J.H., Ji, K.B. et al. Author Correction: Prime editor-mediated correction of a pathogenic mutation in purebred dogs. Sci Rep 12, 15759 (2022). https://doi.org/10.1038/s41598-022-20187-7
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DOI: https://doi.org/10.1038/s41598-022-20187-7
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