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Microglia

Local translation in microglial processes

Nature Neuroscience volume 26, pages 1140–1142 (2023)Cite this article

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Vasek et al. show that microglia perform protein translation in their processes and that this translation is important for the number of processes and formation of phagocytic cups. These findings may provide insight into how microglia respond rapidly to a wide variety of local signals in defined cellular compartments.

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Fig. 1: Microglial local translation.

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Authors and Affiliations

  1. Division of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada

    Haley A. Vecchiarelli & Marie-Ève Tremblay

  2. Centre for Advanced Materials and Related Technology (CAMTEC), University of Victoria, Victoria, British Columbia, Canada

    Marie-Ève Tremblay

  3. Institute for Aging and Lifelong Health, University of Victoria, Victoria, British Columbia, Canada

    Marie-Ève Tremblay

  4. Départment de Médicine Moléculaire, Centre de Recherche du CHU de Québec, Université Laval, Québec City, Québec, Canada

    Marie-Ève Tremblay

  5. Axe Neurosciences, Centre de Recherche du CHU de Québec, Université Laval, Québec City, Québec, Canada

    Marie-Ève Tremblay

  6. Neurology and Neurosurgery Department, McGill University, Montréal, Québec, Canada

    Marie-Ève Tremblay

  7. Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

    Marie-Ève Tremblay

Authors
  1. Haley A. Vecchiarelli
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  2. Marie-Ève Tremblay
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Corresponding authors

Correspondence to Haley A. Vecchiarelli or Marie-Ève Tremblay.

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The authors declare no competing interests.

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Vecchiarelli, H.A., Tremblay, MÈ. Local translation in microglial processes. Nat Neurosci 26, 1140–1142 (2023). https://doi.org/10.1038/s41593-023-01370-z

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