Robust conclusions require rigorous statistics. In 2009 a seminal paper described the dangers and prevalence of double-dipping in neuroscience. Ten years on, I consider progress toward statistical rigor in neuroimaging.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Translational Psychiatry Open Access 20 March 2020
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Kriegeskorte, N., Simmons, W. K., Bellgowan, P. S. F. & Baker, C. I. Nat. Neurosci. 12, 535–540 (2009).
Ioannidis, J. P. PLoS Med. 2, e124 (2005).
Poldrack, R. A. et al. Nat. Rev. Neurosci. 18, 115–126 (2017).
Vul, E., Harris, C., Winkielman, P. & Pashler, H. Perspect. Psychol. Sci. 4, 274–290 (2009).
Bennett, C. M., Miller, M. B. & Wolford, G. L. Neural correlates of interspecies perspective taking in the post-mortem Atlantic Salmon: an argument for multiple comparisons correction. NeuroImage 47, S125 (2009).
Button, K. S. et al. Nat. Rev. Neurosci. 14, 365–376 (2013).
Thompson, P. M. et al. Alzheimer’s Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study (SYS) Group. Brain Imaging Behav. 8, 153–182 (2014).
Biswal, B. B. et al. Proc. Natl. Acad. Sci. USA 107, 4734–4739 (2010).
Nichols, T. E. et al. Nat. Neurosci. 20, 299–303 (2017).
Dickersin, K. & Rennie, D. J. Am. Med. Assoc. 290, 516–523 (2003).
Munafò, M. R. et al. Nat. Hum. Behav. 1, 0021 (2017).
Carp, J. Neuroimage 63, 289–300 (2012).
Guo, Q. et al. PLoS One 9, e94412 (2014).
Carp, J. Front. Neurosci. 6, 149 (2012).
Ioannidis, J. P., Tarone, R. & McLaughlin, J. K. Epidemiology 22, 450–456 (2011).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Button, K.S. Double-dipping revisited. Nat Neurosci 22, 688–690 (2019). https://doi.org/10.1038/s41593-019-0398-z
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41593-019-0398-z
This article is cited by
-
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Translational Psychiatry (2020)