Same lesson, varied choices by frontal cortex

In an unfamiliar situation, animals display variable choice behavior. Based on computational modeling and empirical data, a new study suggests that the variability in decision-making across individuals is driven by differences in internal neural dynamics in the medial frontal cortex.

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Fig. 1: Internal neural dynamics in the medial frontal cortex as a determinant of choice behavior.


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This work was supported by the National Institute of Mental Health (R01 MH112750 and R21 MH118596) and by a Kavli Institute for Neuroscience Postdoctoral Fellowship.

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Correspondence to Alex C. Kwan.

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Atilgan, H., Kwan, A.C. Same lesson, varied choices by frontal cortex. Nat Neurosci 21, 1648–1650 (2018).

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