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An open-source platform for analyzing and sharing worm-behavior data

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Fig. 1: Schematic of the searchable database and Tierpsy analysis pipeline.

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Acknowledgements

This work was supported by the MRC through grant MC-A658-5TY30 to A.E.X.B. Q.C. is supported by an ERC Starting Grant (NeuroAge 242666), a Research Councils UK Fellowship, and the University of London Central Research Fund. Some strains were provided by the CGC, which is funded by the NIH Office of Research Infrastructure Programs (P40 OD010440).

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Contributions

A.J. wrote Tierpsy Tracker and analyzed data; M.C. wrote WCON viewer, the database, and OpenWorm Analysis Toolbox; C.W.L. wrote the database, web interface, and WCON viewer; J.H. wrote the MATLAB WCON viewer and OpenWorm Analysis Toolbox; K.L. wrote stage-alignment code; C.N.M. collected data; E.Y. wrote the skeletonization algorithm and stage-alignment code; L.J.G. collected data; C.L. contributed strains and planned experiments; Q.C. contributed strains and planned experiments; W.R.S. planned the study; E.A.A.N. contributed strains and planned experiments; R.K. designed WCON and wrote several readers; A.E.X.B. planned the study and wrote the manuscript.

Corresponding author

Correspondence to André E. X. Brown.

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The authors declare no competing interests.

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Supplementary Software

Source code and documentation for Tierpsy Tracker software

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Javer, A., Currie, M., Lee, C.W. et al. An open-source platform for analyzing and sharing worm-behavior data. Nat Methods 15, 645–646 (2018). https://doi.org/10.1038/s41592-018-0112-1

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