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An open-source platform for analyzing and sharing worm-behavior data

Nature Methods volume 15, pages645–646(2018)Cite this article

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Fig. 1: Schematic of the searchable database and Tierpsy analysis pipeline.

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Acknowledgements

This work was supported by the MRC through grant MC-A658-5TY30 to A.E.X.B. Q.C. is supported by an ERC Starting Grant (NeuroAge 242666), a Research Councils UK Fellowship, and the University of London Central Research Fund. Some strains were provided by the CGC, which is funded by the NIH Office of Research Infrastructure Programs (P40 OD010440).

Author information

Affiliations

  1. MRC London Institute of Medical Sciences, London, UK

    Avelino Javer, Kezhi Li & André E. X. Brown

  2. Institute of Clinical Sciences, Imperial College London, London, UK

    Avelino Javer, Kezhi Li & André E. X. Brown

  3. OpenWorm Foundation, San Diego, CA, USA

    Michael Currie, Chee Wai Lee & Jim Hokanson

  4. Department of Biomedical Engineering, Duke University, Durham, NC, USA

    Jim Hokanson

  5. European Research Institute for the Biology of Ageing, University of Groningen, Groningen, the Netherlands

    Céline N. Martineau & Ellen A. A. Nollen

  6. Department of Biological Sciences, Columbia University, New York, NY, USA

    Eviatar Yemini

  7. MRC Laboratory of Molecular Biology, Cambridge, UK

    Laura J. Grundy & William R. Schafer

  8. Department of Biology, City College of the City University of New York, New York, NY, USA

    Chris Li

  9. Centre for Developmental Neurobiology, King’s College London, London, UK

    QueeLim Ch’ng

  10. Calico Life Sciences LLC, South San Francisco, CA, USA

    Rex Kerr

Authors
  1. Avelino Javer
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  2. Michael Currie
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  3. Chee Wai Lee
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  4. Jim Hokanson
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  5. Kezhi Li
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  6. Céline N. Martineau
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  7. Eviatar Yemini
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  8. Laura J. Grundy
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  9. Chris Li
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  10. QueeLim Ch’ng
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  11. William R. Schafer
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  12. Ellen A. A. Nollen
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  13. Rex Kerr
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  14. André E. X. Brown
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Contributions

A.J. wrote Tierpsy Tracker and analyzed data; M.C. wrote WCON viewer, the database, and OpenWorm Analysis Toolbox; C.W.L. wrote the database, web interface, and WCON viewer; J.H. wrote the MATLAB WCON viewer and OpenWorm Analysis Toolbox; K.L. wrote stage-alignment code; C.N.M. collected data; E.Y. wrote the skeletonization algorithm and stage-alignment code; L.J.G. collected data; C.L. contributed strains and planned experiments; Q.C. contributed strains and planned experiments; W.R.S. planned the study; E.A.A.N. contributed strains and planned experiments; R.K. designed WCON and wrote several readers; A.E.X.B. planned the study and wrote the manuscript.

Corresponding author

Correspondence to André E. X. Brown.

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The authors declare no competing interests.

Supplementary information

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Reporting Summary

Supplementary Software

Source code and documentation for Tierpsy Tracker software

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Javer, A., Currie, M., Lee, C.W. et al. An open-source platform for analyzing and sharing worm-behavior data. Nat Methods 15, 645–646 (2018). https://doi.org/10.1038/s41592-018-0112-1

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