A longitudinal multiomic dataset was assembled to characterize the immune landscape in myocardial infarction and chronic coronary syndromes. Multiomics factor analysis (MOFA) revealed immune signatures that associate with disease stage or treatment outcomes. This work opens new directions for future mechanistic and clinical studies on coronary artery disease and myocardial infarction.
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References
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This is a summary of: Pekayvaz, K. et al. Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nat. Med. https://doi.org/10.1038/s41591-024-02953-4 (2024).
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Immune signatures of disease stages and outcomes in myocardial infarction. Nat Med (2024). https://doi.org/10.1038/s41591-024-02954-3
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DOI: https://doi.org/10.1038/s41591-024-02954-3
