Correction to: Nature Medicine https://doi.org/10.1038/s41591-023-02597-w, published online 15 October 2023.

In the originally published version of this article, the labels in the Fig. 2 key for panels b and f (now shown as “Tirzepatide MTD” and “Placebo” for the inverted blue triangle and white box, respectively) were swapped. This error has been corrected in the HTML and PDF versions of the article.