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Longitudinal analysis shows how microbiome changes might influence responses to immune checkpoint blockade

Longitudinal analysis of stool samples reveals new insights into how the gut microbiome changes during immunotherapy. These findings could inform the application of microbiome-targeted interventions to maximize the outcomes of immune checkpoint blockade.

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Fig. 1: Divergent signals in mono versus combination ICB therapy.

References

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This is a summary of: Björk, J. R. et al. Longitudinal gut microbiome changes in immune checkpoint blockade-treated advanced melanoma. Nat. Med. https://doi.org/10.1038/s41591-024-02803-3 (2024).

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Longitudinal analysis shows how microbiome changes might influence responses to immune checkpoint blockade. Nat Med 30, 644–645 (2024). https://doi.org/10.1038/s41591-024-02830-0

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