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Infectious diseases

Integrating vaccines and monoclonal antibodies into malaria prevention

Two malaria vaccines are approved and several prophylactic antibodies are in development, but a combination of strategies tailored to different epidemiological situations will be needed if malaria is to be eliminated.

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Fig. 1: The malaria life cycle and targets for monoclonal antibodies.

References

  1. World Health Organization. WHO Guidelines for Malaria 2023 https://go.nature.com/48zjClh (2023).

  2. Nussenzweig, R. et al. Mil. Med. 134, 1176–1182 (1969).

    Article  CAS  PubMed  Google Scholar 

  3. Clyde, D. F. et al. Am. J. Med. Sci. 266, 169–177 (1973).

    Article  CAS  PubMed  Google Scholar 

  4. Gaudinski, M. R. et al. N. Engl. J. Med. 385, 803–814 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Wu, R. L. et al. N. Engl. J. Med. 387, 397–407 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Kayentao, K. et al. N. Engl. J. Med. 377, 1833–1842 (2022).

    Article  Google Scholar 

  7. Williams, K. L. et al. Nat. Med. https://doi.org/10.1038/s41591-023-02659-z (2024).

    Article  PubMed  Google Scholar 

  8. Regules, J. A. et al. J. Infect. Dis. 214, 732–772 (2016).

    Article  Google Scholar 

  9. World Health Organization. World Malaria Report 2023 https://go.nature.com/48ummR6 (2023).

  10. Kapulu, M. C. et al. JCI Insight 6, e146443 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  11. World Health Organizaton. Monoclonal Antibodies for Malaria Prevention https://go.nature.com/3RLKwj0 (2023).

  12. Stanisic, D. I. et al. BioDrugs 37, 737–756 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Terrie E. Taylor.

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Taylor, T.E., Osier, F. Integrating vaccines and monoclonal antibodies into malaria prevention. Nat Med 30, 37–38 (2024). https://doi.org/10.1038/s41591-023-02745-2

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