A spatially coupled, individual-based simulation of malaria in Rwanda was used to evaluate changes in drug policy in response to artemisinin-resistant Plasmodium falciparum. Our findings suggest that the deployment of multiple first-line therapies has the potential to reduce treatment failures and slow the fixation of resistant alleles in populations.
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References
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This is a summary of: Zupko, R. J. et al. Modeling policy interventions for slowing the spread of artemisinin-resistant pfkelch R561H mutations in Rwanda. Nat. Med. https://doi.org/10.1038/s41591-023-02551-w (2023).
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Modeling to guide drug policy response to artemisinin-resistant malaria in Rwanda. Nat Med 29, 2716–2717 (2023). https://doi.org/10.1038/s41591-023-02619-7
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DOI: https://doi.org/10.1038/s41591-023-02619-7