By using several large population-based and clinical neuroimaging cohorts, we identified a shared neural basis for several mental disorders, namely the neuropsychopathological factor. This genetically determined factor might represent a delayed development of prefrontal brain neural circuits, leading to poor executive function.
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This is a summary of: Xie, C. et al. A shared neural basis underlying psychiatric comorbidity. Nat. Med. https://doi.org/10.1038/s41591-023-02317-4 (2023).
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A general neuropsychopathological factor underlying many mental illnesses. Nat Med 29, 1072–1073 (2023). https://doi.org/10.1038/s41591-023-02319-2
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DOI: https://doi.org/10.1038/s41591-023-02319-2