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CARDIOVASCULAR DISEASE

Before the heart attack

Nature Medicine volume 28, pages 237–238 (2022)Cite this article

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An Author Correction to this article was published on 09 March 2022

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Integrated analysis of microbiome and metabolome profiles in unique cohorts reveals early and late markers of the transition towards ischemic heart disease.

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Fig. 1: Overview of changes in microbial pathways in different strata of healthy individuals, metabolically matched control individuals (with metabolic dysregulation but without IHD) and patients with IHD.

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Author notes

  1. These authors contributed equally: Ellen E. Blaak, Willem M. de Vos.

Authors and Affiliations

  1. Department of Human Biology, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands

    Ellen E. Blaak

  2. Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

    Willem M. de Vos

  3. Laboratory of Microbiology, Wageningen University, Wageningen, the Netherlands

    Willem M. de Vos

Authors
  1. Ellen E. Blaak
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  2. Willem M. de Vos
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Corresponding author

Correspondence to Ellen E. Blaak.

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Competing interests

W.M.d.V. is a cofounder of and has stock in A-mansia Biotech, which is commercializing the gut bacterium Akkermansia muciniphila. E.E.B. declares no competing interests.

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Blaak, E.E., de Vos, W.M. Before the heart attack. Nat Med 28, 237–238 (2022). https://doi.org/10.1038/s41591-022-01685-7

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