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CLINICAL TRIALS

Beta cell preservation in patients with type 1 diabetes

Nature Medicine volume 24, pages 1089–1090 (2018)Cite this article

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The calcium channel blocker verapamil preserves beta cells in a clinical trial of individuals with adult-onset type 1 diabetes.

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Fig. 1: Verapamil restores beta cell function.

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Acknowledgements

D.Z.I.C. receives funding from by the Juvenile Diabetes Research Foundation (JDRF) (The Canadian Study of Longevity in Diabetes, Operating Grant No. 17-2013-312), the Canadian Diabetes Association and the CIHR–JDRF SPOR operating grant and the Banting and Best Diabetes Centre. He is also the recipient of a University of Toronto Department of Medicine Merit Award. T.K.T.L. is funded by a Canadian Institutes of Health Research (CIHR) Foundation Grant (FDN-143204) and a Canadian Diabetes Association Operating Grant (OG-3-15-4901-TL). T.K.T.L holds the John Kitson McIvor (1915-1942) Endowed Chair in Diabetes Research and the Canada Research Chair in Diabetes and Obesity.

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Authors and Affiliations

  1. Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada

    Tony K. T. Lam & David Z. I. Cherney

  2. Department of Physiology, University of Toronto, Toronto, Ontario, Canada

    Tony K. T. Lam & David Z. I. Cherney

  3. Department of Medicine, University of Toronto, Toronto, Ontario, Canada

    Tony K. T. Lam & David Z. I. Cherney

  4. Banting and Best Diabetes Centre, Toronto, Ontario, Canada

    Tony K. T. Lam & David Z. I. Cherney

  5. Department of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada

    David Z. I. Cherney

Authors
  1. Tony K. T. Lam
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T.K.T.L. and D.Z.I.C. prepared the manuscript and take responsibility for the integrity and accuracy of the manuscript.

Corresponding author

Correspondence to David Z. I. Cherney.

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Competing interests

D.Z.I.C. has received consulting fees or speaking honorarium or both from Janssen, Boehringer Ingelheim-Eli, Lilly, AstraZeneca, Merck and Sanofi and has received operating funds from Janssen, Boehringer Ingelheim-Eli, Lilly, AstraZeneca and Merck.

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Lam, T.K.T., Cherney, D.Z.I. Beta cell preservation in patients with type 1 diabetes. Nat Med 24, 1089–1090 (2018). https://doi.org/10.1038/s41591-018-0144-1

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