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Microbiome metabolomics reveals new drivers of human liver steatosis

An integrative multiomics approach in nondiabetic obese women identifies phenylacetate as a microbial metabolite contributing to the accumulation of lipids in the liver and hence to nonalcoholic steatohepatitis.

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Fig. 1: The gut microbiota contributes to hepatic steatosis.

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Correspondence to Nathalie M. Delzenne.

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Delzenne, N.M., Bindels, L.B. Microbiome metabolomics reveals new drivers of human liver steatosis. Nat Med 24, 906–907 (2018).

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