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Dendritic cells

A new step in understanding mouse cDC ontogeny

Understanding the ontogeny of conventional dendritic cells (cDCs) is a major aim in the field. The fate of progenitors of the recently described subsets of mouse cDC2s (cDC2A and cDC2B) is determined in the bone marrow.

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Fig. 1: Models of mDC differentiation.

References

  1. Brown, C. C. et al. Cell 179, 846–863.e24 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Tussiwand, R. et al. Immunity 42, 916–928 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Minutti, C. M. et al. Nat. Immunol. https://doi.org/10.1038/s41590-024-01745-9 (2024).

    Article  PubMed  Google Scholar 

  4. See, P. et al. Science 356, eaag3009 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Dress, R. J. et al. Nat. Immunol. 20, 852–864 (2019).

    Article  CAS  PubMed  Google Scholar 

  6. Schlitzer, A. et al. Nat. Immunol. 16, 718–728 (2015).

    Article  CAS  PubMed  Google Scholar 

  7. Villani, A.-C. et al. Science 356, eaah4573 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Dutertre, C.-A. et al. Immunity 51, 573–589.e8 (2019).

    Article  CAS  PubMed  Google Scholar 

  9. Cytlak, U. et al. Immunity 53, 353–370.e8 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Bourdely, P. et al. Immunity 53, 335–352.e8 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Liu, Z. et al. Immunity 56, 1761–1777.e6 (2023).

    Article  CAS  PubMed  Google Scholar 

  12. Maier, B. et al. Nature 580, 257–262 (2020).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Download references

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Correspondence to Charles-Antoine Dutertre.

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Dutertre, CA. A new step in understanding mouse cDC ontogeny. Nat Immunol 25, 383–384 (2024). https://doi.org/10.1038/s41590-024-01763-7

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