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Human hematopoiesis

Reading the Ts and DCs of thymopoiesis

Nature Immunology volume 24, pages 385–386 (2023)Cite this article

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Dendritic-cell-biased thymic seeding progenitors provide stromal support for early T cell development through the expression of membrane-bound TNF.

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Fig. 1: Two models of intrathymic differentiation of DC from TSPs.

References

  1. Wang, H. & Zúñiga-Pflücker, J. C. Front. Immunol. 13, 885280 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Liang, K. L. et al. Nat. Immunol. https://doi.org/10.1038/s41590-022-01417-6 (2023).

    Article  PubMed  Google Scholar 

  3. Guilliams, M., Mildner, A. & Yona, S. Immunity 49, 595–613 (2018).

    Article  CAS  PubMed  Google Scholar 

  4. Lavaert, M. et al. Immunity 52, 1088–1104.e6 (2020).

    Article  CAS  PubMed  Google Scholar 

  5. Le, J. et al. Immunity 52, 1105–1118.e9 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Cordes, M. et al. Sci. Immunol. 7, eade0182 (2022).

    Article  CAS  PubMed  Google Scholar 

  7. Martín-Gayo, E. et al. J. Exp. Med. 214, 3361–3379 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Bigley, V. et al. J. Allergy Clin. Immunol. 141, 2234–2248 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Cytlak, U. et al. Immunity 53, 353–370.e8 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Dzhagalov, I. & Phee, H. Cell Mol. Life Sci. 69, 663–682 (2012).

    Article  CAS  PubMed  Google Scholar 

  11. Vollmann, E. H. et al. Nat. Commun. 12, 6230 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Zhou, T. A. et al. eLife 11, e75148 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

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Authors and Affiliations

  1. Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK

    Matthew Collin

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  1. Matthew Collin
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Correspondence to Matthew Collin.

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The author declares no competing interests.

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Collin, M. Reading the Ts and DCs of thymopoiesis. Nat Immunol 24, 385–386 (2023). https://doi.org/10.1038/s41590-023-01439-8

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