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Lymphocyte lineages

Resident memory T cells develop regional dialects

Nature Immunology volume 24, pages 209–210 (2023)Cite this article

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Human resident memory T (TRM) cells clonally segregate in distinct tissues, with gene expression signatures tailored to those sites. Hence, beyond a shared language of residency, TRM cells may acquire local dialects to provide site-specific immunity.

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Authors and Affiliations

  1. Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA

    Nicholas J. Maurice & Stephen C. Jameson

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  1. Nicholas J. Maurice
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  2. Stephen C. Jameson
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Correspondence to Stephen C. Jameson.

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The authors declare no competing interests.

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Maurice, N.J., Jameson, S.C. Resident memory T cells develop regional dialects. Nat Immunol 24, 209–210 (2023). https://doi.org/10.1038/s41590-022-01416-7

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