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IMMUNE SURVEILLANCE

γδ T cells monitor tissue health

Crosstalk between the dendritic epidermal γδ T cell (DETC) T cell receptor and Skint1 expressed by keratinocytes at steady state regulates epidermal barrier function and maintains DETC responsiveness.

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Fig. 1: Epidermal Skint1–DETC interactions maintain immunosurveillance and barrier function.

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Correspondence to Shruti Naik.

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Subudhi, I., Naik, S. γδ T cells monitor tissue health. Nat Immunol 23, 348–349 (2022). https://doi.org/10.1038/s41590-022-01139-9

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  • DOI: https://doi.org/10.1038/s41590-022-01139-9

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