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Aging alters rhythms in immunity

Nature Immunology volume 23, pages 153–154 (2022)Cite this article

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A new study shows that the transcription factor KLF4 has a role in the maintenance of circadian immune responses. Loss of KLF4 activity contributes to the age-associated immune dysfunction.

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Fig. 1: Circadian rhythms have an important role in maintaining macrophage function.

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Authors and Affiliations

  1. Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland

    Annie M. Curtis & Richard G. Carroll

  2. Tissue Engineering Research Group (TERG), RCSI University of Medicine and Health Sciences, Dublin, Ireland

    Annie M. Curtis & Richard G. Carroll

Authors
  1. Annie M. Curtis
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  2. Richard G. Carroll
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Correspondence to Richard G. Carroll.

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The authors declare no competing interests.

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Curtis, A.M., Carroll, R.G. Aging alters rhythms in immunity. Nat Immunol 23, 153–154 (2022). https://doi.org/10.1038/s41590-021-01099-6

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