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The path of the T-bet-ian CD8+ T cells

Nature Immunology volume 22, pages 402–403 (2021)Cite this article

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The eradication of pathogens and establishment of immunological memory depend on the generation of both effector and long-lived memory cells within specialized immune niches. Whole-organ imaging demonstrates that, during viral infection, the fate of CD8+ T cells in lymph nodes is coupled to chemotactic signals controlling their distribution within different microanatomical sites.

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Fig. 1: Regulation of CD8+ T cell differentiation is coupled to the cell’s location.

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Authors and Affiliations

  1. Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel

    Liat Stoler-Barak & Ziv Shulman

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  1. Liat Stoler-Barak
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  2. Ziv Shulman
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Correspondence to Ziv Shulman.

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The authors declare no competing interests.

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Stoler-Barak, L., Shulman, Z. The path of the T-bet-ian CD8+ T cells. Nat Immunol 22, 402–403 (2021). https://doi.org/10.1038/s41590-021-00905-5

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