A new study has identified various previously unknown mutations in the genes encoding human and mouse A20 that affect its phosphorylation and its function as an inhibitor of the transcription factor NF-κB, with implications for immunity and inflammatory disease.
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Martens, A., van Loo, G. A20 phosphorylation controls A20 function. Nat Immunol 20, 1261–1262 (2019). https://doi.org/10.1038/s41590-019-0481-3
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DOI: https://doi.org/10.1038/s41590-019-0481-3
