In response to epithelial DNA damage, tissue-resident γδ T cells initiate and shape a tumor-protective IgE response that requires CD4+ T cells and immune effector cells expressing the high-affinity IgE receptor FcεRI.
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McGraw, J.M., Havran, W.L. γδ T cells and IgE team up to prevent tumors. Nat Immunol 19, 793–795 (2018). https://doi.org/10.1038/s41590-018-0167-2
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DOI: https://doi.org/10.1038/s41590-018-0167-2
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