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MACROPHAGE POLARIZATION

TORching a semaphore for alternative macrophage activation

Nature Immunologyvolume 19pages512514 (2018) | Download Citation

The metabolic master regulator mTORC1 is shown to promote alternative macrophage activation via Semaphorin 6D reverse signaling and reprogramming of lipid metabolism.

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Author information

Affiliations

  1. Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria

    • Jayne Louise Wilson
    •  & Thomas Weichhart

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Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Thomas Weichhart.

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DOI

https://doi.org/10.1038/s41590-018-0117-z

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