Autoreactive T cells exclusively recognize the roof of the binding groove of the antigen-presenting molecule CD1c after it has caved in on short headless self lipids.
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Zajonc, D.M. CD1c caves in on lipids. Nat Immunol 19, 322–324 (2018). https://doi.org/10.1038/s41590-018-0074-6
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DOI: https://doi.org/10.1038/s41590-018-0074-6