CANCER IMMUNOLOGY

Cancer cells deliver a suppressive cargo

Tumor cells downregulate type I interferon responses through their delivery of immunomodulatory exosomes, which has implications for antiviral suppression in people with cancer.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    Gao, L. et al. Nat. Immunol. https://doi.org/10.1038/s41590-017-0043-5 (2018).

  2. 2.

    Benito-Martin, A., Di Giannatale, A., Ceder, S. & Peinado, H. Front. Immunol. 6, 66 (2015).

  3. 3.

    Whiteside, T. L. Biochem. Soc. Trans. 41, 245–251 (2013).

  4. 4.

    Bergstroem, B. et al. J. Biol. Chem. 285, 24904–24914 (2010).

  5. 5.

    Zhang, B. et al. Cell Res. 19, 412–428 (2009).

  6. 6.

    Qian, B. Z. & Pollard, J. W. Cell 141, 39–51 (2010).

  7. 7.

    Biswas, S. K. & Mantovani, A. Nat. Immunol. 11, 889–896 (2010).

  8. 8.

    Dunn, G. P., Koebel, C. M. & Schreiber, R. D. Nat. Rev. Immunol. 6, 836–848 (2006).

  9. 9.

    Woo, S. R., Corrales, L. & Gajewski, T. F. Annu. Rev. Immunol. 33, 445–474 (2015).

  10. 10.

    Shen, Y. J. et al. Cell Rep. 11, 460–473 (2015).

  11. 11.

    Ho, S. S. et al. Immunity 44, 1177–1189 (2016).

  12. 12.

    Ng, K. W., Marshall, E. A., Bell, J. C. & Lam, W. L. Trends Immunol. 39, 44–54 (2018).

Download references

Author information

Correspondence to Akinori Takaoka.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Takaoka, A. Cancer cells deliver a suppressive cargo. Nat Immunol 19, 207–208 (2018) doi:10.1038/s41590-018-0050-1

Download citation