DNA-encoded libraries are a powerful tool to identify novel chemical inducers of proximity such as targeted protein degraders, even without a known binder for the target protein.
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Andrea Testa is an employee of Amphista Therapeutics Ltd.
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Testa, A. Affinity for both sides. Nat Chem Biol 20, 134–135 (2024). https://doi.org/10.1038/s41589-023-01473-5
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DOI: https://doi.org/10.1038/s41589-023-01473-5