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A new RNA performs old chemistry

Natural self-cleaving RNAs employ a wide range of catalytic strategies, but it is not known whether artificial ribozymes are capable of the same catalytic diversity. New structures of a methyltransferase ribozyme reveal the potential variety of RNA reactions and mechanisms.

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Fig. 1: Catalysis by MTR1.


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Correspondence to Scott A. Strobel.

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Hiller, D.A., Strobel, S.A. A new RNA performs old chemistry. Nat Chem Biol 18, 438–439 (2022).

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