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Scrutinizing disease states and regulation in human microglia

Single-cell and bulk transcriptomics of adult human microglia from a population of individuals reveals activated states across several brain disorders and maps Alzheimer’s disease variants to microglia-enriched genes.

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Fig. 1: Molecular mapping of human microglia.


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Correspondence to Sergiu P. Pașca.

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Kelley, K.W., Pașca, S.P. Scrutinizing disease states and regulation in human microglia. Nat Genet 53, 766–767 (2021).

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