Most plant hormone sensors, including the abscisic acid receptor PYR1, function through chemically induced dimerization. Using computationally designed libraries of PYR1, we created high-affinity receptors for 21 structurally diverse ligands, setting the stage for large-scale small-molecule biosensor development
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This is a summary of: Beltrán, J. et al. Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds. Nat. Biotechnol. https://doi.org/10.1038/s41587-022-01364-5 (2022).
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Plant hormone sensors as scaffolds for biosensor design. Nat Biotechnol 40, 1772–1773 (2022). https://doi.org/10.1038/s41587-022-01373-4
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DOI: https://doi.org/10.1038/s41587-022-01373-4
