This year could see the first trials of therapies employing base editing that introduce precise single-nucleotide changes into patient genomes.
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Change history
07 June 2022
In the version of this article initially published, the quote in the second paragraph in Box 2 appeared without the contextual text “addressing the similar issue of foreign Cas9 protein,” which has now been amended.
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Eisenstein, M. Base editing marches on the clinic. Nat Biotechnol 40, 623–625 (2022). https://doi.org/10.1038/s41587-022-01326-x
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DOI: https://doi.org/10.1038/s41587-022-01326-x
