By quantifying thousands of proteins in tumor cells in an unbiased manner, Deep Visual Proteomics uncovers mechanisms that drive tumor evolution and reveals new therapeutic targets. The method incorporates advanced microscopy, artificial intelligence and ultra-high-sensitivity proteomics to characterize individual cell identities.
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References
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This is a summary of: Mund, A. et al. Deep Visual Proteomics defines single-cell identity and heterogeneity. Nat. Biotechnol. https://doi.org/10.1038/s41587-022-01302-5 (2022).
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Spatial characterization of single tumor cells by proteomics. Nat Biotechnol 40, 1186–1187 (2022). https://doi.org/10.1038/s41587-022-01321-2
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DOI: https://doi.org/10.1038/s41587-022-01321-2